Gene polymorphisms in leptin and its receptor and the response to growth hormone treatment in patients with idiopathic growth hormone deficiency

This research aimed to analyze the relationships between genetic polymorphisms of leptin/receptor genes and scientific/biochemical traits in kids with progress hormone deficiency (GHD). Ninety-three GHD kids and 69 age-matched regular controls have been enrolled. Anthropometric measurements, bone age, and laboratory check outcomes have been obtained. Polymorphisms within the LEP gene promoter locus (LEP-2548, rs7799039) and LEPR genes (Ok109R, …

Gene polymorphisms in leptin and its receptor and the response to growth hormone treatment in patients with idiopathic growth hormone deficiencyContinue reading